The properties of calcium elenolate so encouraged the people at Upjohn that they spent much time and money in an attempt to synthesize and patent a "miracle" antibiotic. But, they discovered a problem that they were unable to overcome.

Although calcium elenolate showed unequaled therapeutic effect invitro (in a test tube), it was discovered that it was only effective in vivo (in the body) for a few minutes. They determined that calcium elenolate binds to proteins in the blood stream, thus inactivating it.

After three years of trying to solve the problem without success, Upjohn abandoned the project.

Unraveling the Mystery
Several years ago East Park Research discovered a breakthrough that opened the way for application of a natural Olive Leaf Extract product.

Further research determined that there are two forms of elenolic acid  produced by the olive leaf. Biochemists call these two forms stereo isomers. The best way to understand stereo isomers is to look at human hands.

When clasping your hands together, your fingers and thumb are identical, amiror image. However if you place your right hand palm side down over the back of your left hand, you can see they are completely dissimilar. So it is with stereo isomers.

Many organic compounds have stereo isomers. Amino acids have left and right handed molecules called leverotate and dextrorotate respectfully. For example, if one looks on the ingredient listing of a protein supplement, one will see l-arginine and l-carnitine. The "l" signifies the left-handed molecule.

Nature also produces an equal amount of d-arginine and d-carnitine but the designer of life chose only to use left-handed amino acids to make DNA, RNA and other life proteins. Left-handed amino acids can connect to other left-handed amino acids to form more complex compounds. In like manner, left-handed elenolic acid combines with left-handed amino acids and proteins in the blood.

Because of their configuration, right-handed elenolic acid does not bind to the left-handed amino acids and proteins in the blood. The way scientists determine whether a molecule is left-handed or right-handed is in the way the molecule reflects polarized light. l-elenolic acid  molecules reflect polarized light to the left and d-elenolic acid  molecules reflect to the right.

The Final Breakthrough
Using the previous biochemical research as a starting point, East Park Research began to look for the secret of developing an Olive Leaf Extract that works in the body longer than a few minutes.

After more than three years, and hundreds of thousands of dollars, East Park Research discovered the solution to the mystery. East Park Research, Inc. has now obtained patent protection for their proprietary extraction process. That process concentrates right-reflecting (the effective form) of elenolic acid in a natural olive leaf product called d-LENOLATE

Since that time, word has spread about the power of the East ParkTM Olive Leaf Extract d-LENOLATE and many other companies are starting to manufacture an olive leaf product. Many of these companies have focused their attention on oleuropein content. Although oleuropein has many benefits for health, it is the concentration of  d-elenolic acid  that provides extended protection. Only East Park Research, Inc. has a patented process for concentrating d-elenolic acid.

East Park Research, Inc. has now changed the product name for the extract produced under this patent from East ParkTM Olive Leaf Extract to East ParkTM d-LENOLATE.